SeleRNA

Our Team

World-class researchers pioneering the future of cardiac therapeutics

Lior Zangi, Ph.D.

Founder & Principal Investigator
Associate Professor of Cardiology
Associate Professor of Genetics and Genomic Sciences
Chan Soon-Shiong Professorship in Cardiovascular Research
Icahn School of Medicine at Mount Sinai

Dr. Lior Zangi is a pioneering researcher in cardiac regeneration and modified mRNA therapeutics. His groundbreaking research focuses on methods for delivering modified mRNA (modRNA) to the heart to induce cardiac and cardiovascular regeneration and protection following ischemic injury.

His published work represents several world-firsts in the field: demonstrating modRNA delivery into cardiac and skeletal muscle, pioneering the use of modRNA to treat ischemic heart disease, and showing that modRNA technology can generate cardiac repair after heart attack and prevent heart failure formation in both small and large animals.

Dr. Zangi holds tenure at Mount Sinai and serves as the Chan Soon-Shiong Professor in Cardiovascular Research, leading efforts to translate cutting-edge modRNA science into life-changing therapies for patients with heart disease.

Research Focus & Achievements

  • First demonstration of modRNA delivery to cardiac and skeletal muscle
  • Pioneer in using modRNA to treat ischemic heart disease
  • Proven cardiac repair and heart failure prevention in animal models
  • Developer of cardiomyocyte-selective translation platforms
  • 35+ peer-reviewed publications in leading journals
  • Expert in lipid-nanoparticle delivery to cardiac tissue